The field of artificial life has a rich history of highly interdisciplinary research investigating methods for simulating and synthesizing living systems, drawing from research in diverse fields such as evolutionary computation, philosophy, and artificial chemistry. This volume contains the proceedings from the 2020 conference on Artificial Life, which was supposed to be held in Montreal, Canada, but was instead held virtually. The theme for this year's conference is “New Frontiers in AI: What can ALife offer AI?”, with selected works exploring both the possibilities and challenges of combining revolutionary ideas originating in artificial life with modern artificial intelligence methods.